The Palestine Children's Relief Fund is a registered non-political, non-profit, 501(c)3 tax-exempt organization that was established in 1991 by concerned people in the U.S. to address the medical and humanitarian crisis facing Palestinian youths in the Middle East. It has since expanded to help suffering children from other Middle Eastern nations, based only on their medical needs. The P.C.R.F. helps to locate free medical care for children from the Middle East who are unable to get the necessary and specialized treatment in their homeland.

The main objective of the P.C.R.F. is to identify and treat every child in the Middle East in need of specialized surgery not available to them locally.